ACT001 suppresses ox-LDL-mediated macrophage ferroptosis via activating the NRF2 pathway: An in vitro mechanistic study relevant to atherosclerosis
Oxidized low-density lipoprotein (ox-LDL) is a key inducer of ferroptosis, which is associated with the progression of atherosclerosis. Macrophages play a notable role in atherosclerosis development, and ferroptosis in these cells contributes to the pathological process of atherosclerosis. However, the potential interv...