Oct 2026
Targeting the HIF-1α-BSG metabolic circuit reverses enzalutamide resistance in prostate cancer.
BACKGROUND Enzalutamide resistance limits durable control of castration-resistant prostate cancer (CRPC), but the mechanisms coordinating metabolic adaptation, cellular plasticity, and residual androgen receptor (AR) signaling remain incompletely understood. We investigated whether BSG, encoding basigin/CD147, contribu...
Xiu-Chen Guo, Jia-Cheng Huang, Zhi-Wei Chen et al.
· Cellular Signalling · 0 citations