GsMTx4 Alleviates Knee Osteoarthritis by Inhibiting PIEZO1/2-mediated Chondrocyte Apoptosis.
BACKGROUND Knee osteoarthritis (KOA) is a prevalent, disabling degenerative joint disorder featuring progressive articular cartilage loss, persistent chronic pain, and compromised knee mobility. This work aimed to characterize the expression pattern of mechanosensitive ion channels PIEZO1/2 in KOA and explore their pot...