Leptin promotes obesity‑related osteoarthritis progression via CD44/JAK2/STAT3 axis‑mediated chondrocyte apoptosis.
Osteoarthritis (OA), especially obesity‑related OA, is a common joint disease in which leptin serves a notable role; however, the specific mechanism by which leptin promotes obesity‑related OA progression remains unclear. In the present study, human cartilage samples confirmed the association between leptin and obesity...