Yong-Le Tian

Taming the Flexible Eight-Membered Ring: Enantioselective Synthesis of Inherently Chiral Dibenzo[a,e]cyclooctatetraenes Enabled by Pd-Catalyzed Suzuki-Miyaura Cross-Coupling.

Inherently chiral molecules generated by the curvature of planar frameworks represent an emerging class of three-dimensional chiral architectures, yet their catalytic asymmetric synthesis remains highly challenging. Herein, we report a Pd-catalyzed asymmetric Suzuki-Miyaura coupling for the efficient construction of in...