Sep 2026
Sodium tanshinone IIA sulfonate attenuates pulmonary vascular remodeling by targeting DYRK1A in pulmonary hypertension.
BACKGROUND Pulmonary hypertension (PH) is a progressive disorder marked by elevated pulmonary artery (PA) pressure and vascular remodeling, often leading to right heart failure. A key feature is pulmonary artery smooth muscle cells (PASMC) phenotypic switching from a contractile to a synthetic state, which drives media...
Zheng-Wei Dong, Qian-Qian Lu, Zhi-Feng Xue et al.
· Phytomedicine · 0 citations