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Yong-Li Yue

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Open access Aug 2026

MBD3 Knockdown Promotes the Differentiation of Bovine iPSCs into Primordial Germ Cell-like Cells Associated with Altered Bivalent Modification of TGF-β-Related Genes

MBD3 knockdown during bovine iPSC reprogramming significantly enhances the differentiation efficiency of primordial germ cell-like cells (PGCLCs) under a 2D monolayer culture system, providing a mechanistic basis for optimizing bovine iPSC-derived PGCLC protocols through targeted epigenetic modulation.

Wen Yuan, Jing Wang, Wei-Qi Li et al. · 0 citations

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