Bone and cartilage defects represent major clinical challenges, with an increasingly urgent need for effective repair and regeneration. In recent years, small RNA-based regulatory strategies, such as microRNAs (miRNAs) and small interfering RNAs (siRNAs), have emerged as promising candidates for promoting bone and cart...
Conventional periodontitis treatments are constrained by challenges such as antibiotic resistance and inadequate tissue regeneration. Herein, we rationally engineer a robust Fe/Mn bimetallic nanozyme (Fe/Mn-Bzyme) derived from a zeolitic imidazolate framework-8 precursor, featuring atomically asymmetric Fe-Mn dual-atom...
Qi-Tao Yu, Yue Zhan, Qiuyue Liu et al.· Acta Biomaterialia· 0 citations
This case expands the mutational and phenotypic spectrum of TP63-associated HED by describing a previously unreported mutation presenting with a pathological femoral neck fracture and end-stage renal disease.
Guang-Hua Liang, Xiang-Ning Meng, Talante Juma et al.· Medicine· 0 citations
Functional enrichment analysis indicates that BPA-induced NAFLD and OA comorbidity pathways are enriched in muscle cell proliferation, DNA metabolism, and inflammation pathways, indicating that limiting BPA exposure or modulating the RHOB pathway represents a viable approach for intervening in related diseases.