Author

Yong-Qi Zhong

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Preprint Aug 2026

From Test Performance to Risk-Based Effect Sizes: A Unified Wald-Type Framework to Design Clinical Validation Studies for Binary and Survival Outcomes

Close-form links from sensitivity, specificity, and disease prevalence to predictive risks, risk contrasts, and Wald-type variance, power, and sample-size formulas for binary and fixed-horizon survival outcomes for binary and fixed-horizon survival outcomes are provided.

Yong-Qi Zhong, A. Hartman, Jing Zhang · 0 citations