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Author

Yong Ryoul Yang

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3 papers indexed here

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Open access Sep 2026

N-terminal thrombospondin-1 enhances muscle function and tissue-specific metabolic adaptation in response to exercise and cold exposure

Exercise and cold exposure elicit partly overlapping metabolic adaptations through distinct mechanisms. Here, we sought to identify circulating factors shared by these stimuli. We found that exercise and cold exposure upregulated thrombospondin-1 (TSP1) expression in skeletal muscle and brown adipose tissue (BAT) and i...

M. Kim, Hyun-Jun Jang, Jae Sook Kang et al. · 0 citations
Review Open access Sep 2026

From Regenerative to Degenerative Niche: Multicellular Crosstalk and Population Dynamics in Skeletal Muscle Aging

ABSTRACT Skeletal muscle aging is increasingly recognized as a failure of tissue‐level coordination rather than a consequence of isolated defects in individual cell types. Recent advances in single‐cell, spatial, and multimodal omics have revealed that aging remodels the abundance, functional states, and interactions o...

Seongwan Kim, M. Kim, Yong Ryoul Yang · 0 citations
Open access Jul 2026

CXCL2 is a modifiable driver of sarcopenic inflammation attenuated by exercise in older women: Integrated transcriptomic and experimental evidence.

Human evidence from year-long clinical exercise interventions identified CXCL2 as a modifiable inflammatory mediator linking aging to muscle atrophy and highlights the CXCL2-CXCR2 axis as a promising target for mitigating sarcopenia.

Juyeon Lee, Sung-Wook Chun, Su-Bin Choi et al. · 0 citations

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