B7-H3 (CD276) is broadly overexpressed across solid tumors and plays active roles in immune evasion, tumor angiogenesis, and metabolic reprogramming. As B7-H3-directed antibody–drug conjugates chimeric antigen receptor T-cell therapies, and radioimmunotherapy agents advance through clinical trials, non-invasive whole-b...
Bao-Yan Liu, Ke-Lin Wang, Ke-Wen He et al.· Frontiers in Pharmacology· 0 citations
Multidrug-resistant (MDR) Gram-negative bacteria—particularly carbapenem-resistant Enterobacterales, Pseudomonas aeruginosa and Acinetobacter baumannii—remain among the hardest infections to treat, and Resistance-Nodulation-Division (RND) efflux pumps are central to that resistance, making them a recurring target for a...
Dan-Xia Kong, Bao-Yan Liu, Xing-Chen Ding et al.· Frontiers in Microbiology· 0 citations
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