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Yong-Wei Zhao

2 papers indexed here

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Review Open access Aug 2026

Baseline Uncommon EGFR Mutations in Non–Small-Cell Lung Cancer: Structure–Function Classification and Clinical Evidence Interpretation

In this narrative review, we examine baseline uncommon epidermal growth factor receptor (EGFR) mutations in non–small-cell lung cancer (NSCLC) through a structure–function classification framework and clinical evidence interpretation. Baseline uncommon EGFR mutations are molecularly heterogeneous, and exon-based classi...

Su-Su Yang, Xiu-Qin Ma, Yong-Wei Zhao et al. · 0 citations
Open access Jul 2026

Mechanism for Aromatic Nitration Catalyzed by Cytochrome P450 Enzymes from Rufomycin Biosynthesis

These experiments revealed the intimate and necessary involvement of a histidine residue within the pentapeptide substrate of RufO in supporting effective nitration, with the protonation state of the intermediate compound II proposed to influence the production of nitrated tyrosine over unwanted nitrate formation.

Alicia M. Kirk, Jemma Gullick, Yong-Wei Zhao et al. · 2 citations

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