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Sep 2026

Mechanistic insights into sucralose immunotoxicology: Dose-related modulation of the gut-immune axis in food allergy.

Sucralose is a widely consumed non-caloric sweetener, but its immunotoxicological effects remain poorly defined. Integrated in vitro and in vivo methods were utilized to investigate its immunotoxicological profile. In vitro, sucralose suppressed dendritic cell maturation and IL-6 secretion, promoted the differentiation...

Wen-Yan Li, Qiang Shi, Yi-Fan Nie et al. · 0 citations
Aug 2026

Component-specific interaction between egg ovalbumin and edible oil fume particles in Chinese cooking: conformational remodeling drives changes in digestibility and allergenicity.

Interactions between food processing-derived components and food proteins can markedly alter protein conformation and functional properties. Among them, cooking oil fume particles (COFPs) are widespread contaminants from high-temperature Chinese cooking. This study first compared the effects of COFPs from four common e...

Wei Hu, Ziwen Hao, Shuang-Yan Zheng et al. · 0 citations

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