Open access
Aug 2026
WaaL–WaaP receptor cross-talk drives phage-induced collateral sensitivity to colistin in Salmonella Pullorum
Phage therapy typically fails when bacteria rapidly evolve resistance, yet the inevitable fitness costs of escape mutants remain underexploited. In this study, an iterative and targeted phage-cocktail formulation strategy (ITPFS) was presented and developed. A potent lytic phage, PHZ055, was firstly isolated against a...
Mian-Zhi Wang, Yiwen Ren, Lei Jiang et al.
· Veterinary Research · 0 citations