Author

Yong Yao

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Review Open access Sep 2026

Loss of Heterozygosity in Chromosome 11q13 Covering MEN1 and AIP Associates with Aggressive Features in Pituitary Tumors

Around 10% of pituitary tumors are estimated to be aggressive and associated with poor prognosis. Loss of heterozygosity (LOH) in chromosome 11q13 has been observed in aggressive pituitary tumors (APTs). Both MEN1 and AIP, located on 11q13 with an interval of 2.7 Mb, have been discovered as genetic markers of APTs. We...

Shi Chen, Jia-Qi Qiang, Lin Lu et al. · Health and Metabolism · 0 citations

Sep 2026

COL4A3 Promotes Invasion and act as Biomarker in Pituitary Neuroendocrine Tumor.

Pituitary neuroendocrine tumors (PitNETs) present significant clinical challenges due to unpredictable invasive behavior and lack of reliable molecular predictors. While the extracellular matrix (ECM), particularly type IV collagen, has emerged as a critical mediator of tumor progression, its mechanistic role in PitNET...

Jie Liu, Zhi-Min Li, K. Deng et al. · Endocrine-Related Cancer · 0 citations

Case report Aug 2026

Clinical management challenges of Cushing’s disease associated with double pituitary adenomas: four cases and literature review

DPAs involving a corticotroph component should be considered as a possible explanation for persistent hypercortisolism after TSS when the resected lesion is negative for ACTH and T-PIT and the role of adjunctive molecular imaging remains preliminary.

Di Zhang, Wan Su, Jing-Hua Liu et al. · Endocrine · 0 citations