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Phenolics from Phyllanthus emblica Linn. ameliorate glucose homeostasis and insulin resistance in high-fat diet/streptozotocin-induced type 2 diabetic mice.
Phyllanthus emblica Linn. contains abundant free phenolic (PEFP) and bound phenolic (PEBP), both of which have demonstrated potential antidiabetic activities. However, their comparative hypoglycemic effects and underlying mechanisms remain unclear. This study investigated the effects of PEFP and PEBP using insulin-resi...
Functional role of the diadenylate cyclase gene cdaA in stress responses of the dairy starter Streptococcus thermophilus.
Results showed that cdaA is critical for osmotic and ethanol tolerance but negatively modulates bile salt resistance in S. thermophilus, suggesting that absence of cdaA confers a survival advantage under bile salt stress.