Author

Yongjae Kim

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Jul 2026

Spatial Profiling Links Metabolic Reprogramming and Stromal Fibroblasts to PD-L1-Discordant NSCLC Responses 2309385

Findings establish meCAF-VEGFA-tumor crosstalk as a therapeutic vulnerability and support spatially-resolved tumor-stroma profiling as a prognostic tool beyond PD-L1 for predicting ICI responses.

Yongjae Kim, Seong-Eun Kim, Bokyung Ann et al. · Journal of Immunology · 0 citations

Open access Jul 2026

Spatial Multi-Platform Integration Reveals Distinct Tumor States and Microenvironmental Niches in Colitis-Associated Colorectal Cancer 2309487

The invasive tumor phenotype is associated with CAF and SPP1+ macrophage proximity and SPP1—CD44-mediated signaling, highlighting the tumor microenvironment as a potential therapeutic target in C-CRC.

Yoonho Lee, Yongjae Kim, J. Baek et al. · Journal of Immunology · 0 citations