Per- and polyfluoroalkyl substance (PFAS) exposures have been linked to reduced birth size, but the underlying epigenetic mechanisms remain unclear. Among 296 mother–infant dyads in the Atlanta African American Maternal–Child Cohort (2016–2020), early pregnancy maternal blood samples (8–14 weeks) were processed for s...
You-Ran Tan, Anne L. Dunlop, Todd M. Everson et al.· Environmental Science &...· 0 citations
BACKGROUND
The C8 Science Panel previously conducted studies of perfluorooctanoic acid (PFOA) exposure in Ohio Valley residents, finding probable links with kidney and testicular cancers, raised cholesterol, ulcerative colitis, thyroid disease, and pre-eclampsia. Findings were largely based on a cohort of 32,254 person...
You-Ran Tan, Jonathan N. Hofmann, Vaughn Barry et al.· Environment International· 0 citations
Global analysis of the maternal lipidome during early pregnancy revealed diverse bioactive lipid involvement in the PFAS-SGA association and if antioxidants and anti-inflammatory nutrients would attenuate exposure effects on adverse maternal–child health outcomes.
K. Taibl, Anne L. Dunlop, Paula-Dene C. Nesbeth et al.· Environmental Health Perspec...· 0 citations
Overall, maternal dietary factors may influence susceptibility to PFAS-related fetal growth effects and may modify the inverse associations between prenatal PFAS exposure and birthweight for gestational age z-scores.
Yun-Jie Huang, Dong-Hai Liang, Anne L. Dunlop et al.· Nutrition and Health· 0 citations
The findings in this high PFOA-exposed cohort provide additional epidemiologic evidence of increased kidney and testicular cancer risk, as well as new evidence of associations with thyroid and pancreatic cancers, which have important implications regarding understanding of the carcinogenic potential of PFOA and the can...
Jonathan N. Hofmann, Youran Tan, Vaughn Barry et al.· Environment International· 0 citations
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