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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

You-Yong Yuan

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2 papers indexed here

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Jul 2026

Drug-likeness defects drive carrier-free cyanine-PROTAC self-assembly for tumor-specific protein degradation.

Proteolysis-targeting chimeras (PROTACs) offer a powerful strategy for targeted protein degradation but suffer from poor solubility, bioavailability, and in vivo distribution due to their "beyond rule-of-five" physicochemical properties, severely limiting clinical translation. Here, we transform these intrinsic drug-li...

Zhenhai Pan, Taian Lin, I. Ullah et al. · 0 citations
Sep 2026

Proteolysis-Targeting Chimera-Loaded Hydrogel Dressings Orchestrate Immunoregulation and Angiogenesis to Promote Tissue Regeneration in Large Diabetic Wounds.

The delayed healing of diabetic wounds is primarily attributed to a persistent excessive inflammatory microenvironment and impaired angiogenesis. Here, we identify the STimulator of INterferon Genes (STING) as a key regulator driving this pathological state within the wound milieu. To address this, we developed SD-Gel,...

Wen-Jun Yang, Yan-Dong Zhao, Minjian Liao et al. · 0 citations

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