Author

Youjia Zhong

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Open access Jul 2026

Over-induction of innate immune responses suppresses T cell response to mRNA SARS-CoV-2 vaccination.

It is suggested that future mRNA vaccine design and vaccination regimens should aim to modulate excessive innate immune responses to improve T cell responses to mRNA vaccines.

C. Tay, Clara W. T. Koh, Justin S. G. Ooi et al. · Vaccine · 0 citations

Open access Aug 2026

Vaccination-first immune priming shapes a sustained mRNA vaccine-induced IgG4 class switch that associates with SARS-CoV-2 breakthrough infection risk

The results illustrate an IgG4-dominated immunological signature in both adults and children and highlight that immune priming by prior infection may shape subsequent mRNA vaccine-induced antibody responses.

T. Pongrácz, U. Marking, O. Bladh et al. · Scientific Reports · 0 citations