Author

Y. A. Bin Jardan

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Sep 2026

Structure-Based Virtual Screening and Computational Evaluation of Putative Mushroom-Associated Natural Compounds as Janus Kinase 1 (JAK1) Inhibitors: An In Silico Study.

INTRODUCTION/OBJECTIVE Janus kinase 1 (JAK1) is a key controller and regulator of cytokinemediated immune responses and an effective therapeutic target in autoimmune and inflammatory diseases. In the present study, an in silico workflow was implemented to identify secondary metabolites of mushrooms as prospective JAK1-...

Bushra Shakoor, Ali Irfan, M. T. Muhammed et al. · Current Medicinal Chemistry · 0 citations

Open access Jul 2026

Eudragit S100-coated microbeads of thiolated chitosan/casein for pH-responsive colon-targeted delivery of 6-mercaptopurine

Overall, the Eu-S100@TCh/CS microbead system represents a rationally designed colon-targeted delivery platform with potential to improve local therapeutic efficacy and reduce systemic toxicity.

Huma Hameed, Syed Muhammad Ahmad, Shazia Akram Ghumman et al. · RSC Advances · 0 citations