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Review Oct 2026

Nanoparticle-based senolytic and senomorphic therapies for healthy aging: design principles, translational evidence, and challenges.

Cellular senescence contributes to age-associated tissue dysfunction through persistent growth arrest, metabolic remodeling, and altered communication with immune and stromal cells. Senolytic therapies preferentially eliminate susceptible senescent cells, while senomorphic therapies modulate harmful senescence-associat...

Jia-Bin Huang, Li-Chen Ji, Hui-Hui Jin et al. · 0 citations

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