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Yu-Cai He

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Sep 2026

Modular Whole-Cell Transaminase Cascades for Bioamination of Biomass-Derived Aldehydes through Amino-Donor Regeneration and Pyruvate Removal

The biocatalytic conversion of lignocellulose-derived aldehydes into value-added aromatic and heteroaromatic amines is often restricted by the reversibility of transamination, inefficient amine-donor utilization, pyruvate accumulation, and insufficient intracellular cofactor regeneration. In this study, three modular...

Qi Li, Yu-Yang Hu, Yu Deng et al. · 0 citations
Sep 2026

Valorization of Food Waste and Marine Biomass into 5-(Hydroxymethyl)furfurylamine through the Sustainable Chemobiocatalytic Strategy

A single-vessel two-step chemobiocatalytic strategy was developed for conversion of d-fructose, bread crumbs, and marine biomass (purple laver) into value-added furanic chemicals. A ternary deep eutectic solvent (DES), Be/Gly/MaA, efficiently catalyzed 5-hydroxymethylfurfural (5-HMF) production from d-fructose, bread...

Qi Li, Yu Deng, Yu-Cai He · 0 citations
Aug 2026

Efficient transformation of lignin-derived syringaldehyde to syringyl acetate via tandem catalysis with alcohol dehydrogenase and lipase.

Efficient valorization of lignin-derived aromatics remains a key challenge in sustainable chemistry. Biobased aromatic alcohols and esters are important value-added compounds widely used in fragrances, pharmaceutical intermediates, fine chemicals, and functional materials. In this study, a whole-cell biocatalytic syste...

Hao-Yu Chai, Xin Li, Yu-Cai He et al. · 0 citations
Open access Aug 2026

Niacin Synthesis from 3-Cyanopyridine by Recombinant Escherichia coli: Optimization and Immobilization

Niacin (vitamin B3) is a high-value chemical widely used in the pharmaceutical and food industries. In this study, a recombinant Escherichia coli strain expressing nitrilase from Pseudomonas putida CGMCC3830 was evaluated for the whole-cell biotransformation of high-concentration 3-cyanopyridine to niacin. Molecular do...

Zaiheng Wu, Jing-Yi Zhou, Bo Fan et al. · 0 citations

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