Sep 2026
NFKBIB methylation by SETD3 controls NF-κB-mediated interferon activation during viral infection.
The activation and regulation of type I interferon (IFN-I) is essential for the antiviral response and while epigenetic modifiers are known for regulating cellular signaling and responses by modifying nonhistone substrates, their role in IFN-I signaling remains uncertain. Here, through high-throughput screening, we ide...
Rui-Qi Sun, Bo-Xuan Yin, Li-Lin Zhang et al.
· The FEBS Journal · 0 citations