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Open access Sep 2026

The Efficacy of Adjuvant EGFR-TKI Therapy for Stage IA Lung Adenocarcinoma with EGFR Mutations: A Retrospective Cohort Study.

INTRODUCTION Surgical resection is the standard for early-stage lung adenocarcinoma (LUAD), but recurrence remains a risk for patients with epidermal growth factor receptor (EGFR) mutations. The efficacy of adjuvant EGFR tyrosine kinase inhibitors (EGFR-TKIs) in stage IA LUAD is currently controversial. METHODS This...

Yao-Xi Zhang, Ze-Tao Liu, Qi-Xia Yuan et al. · 1 citation
Open access Aug 2026

BraMARS: An Interpretable Histopathology‐Driven Deep Learning Model for Brain Metastasis Risk Stratification in Surgically Resected Limited‐Stage SCLC

Overall, BraMARS provides a biologically interpretable histopathology‐based framework for estimating subsequent BM risk in resected LS‐SCLC, with potential to support individualized intracranial risk assessment, intensified MRI surveillance, and hypothesis generation for prospective BM‐prevention strategies.

Zi-Jian Yang, Taolue Wang, Shilong Liu et al. · 0 citations

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