Open access
Sep 2026
Thioredoxin reductase-1 facilitates cellular plasticity and stemness mediated by TGF-β1 in non-small cell lung cancer
This study identifies TXNRD1 as a crucial regulator of cellular plasticity and metastasis in NSCLC via the TGF-β1 pathway, suggesting that targeting TXNRD1 may reduce metastatic potential and improve patient survival.
Yaw-Dong Lang, Shin-Yuan Gu, Jou-Ho Shih et al.
· Cancer Biology & Therapy · 0 citations