Aug 2026
Single-cell reanalysis characterizes an Osmr+ astrocyte state and predicts midkine signaling to Cox6b1+ glutamatergic neurons at 24 h after traumatic brain injury.
BACKGROUND Traumatic brain injury (TBI) remains a leading cause of mortality and long-term neurological disability worldwide. The cellular heterogeneity and intercellular communication in the injured brain remain incompletely defined, particularly the astrocyte-neuron crosstalk that could drive potential interventions....
Fu Zhao, Lu-Xi Cao, Jia-Nan Chen et al.
· Brain Research · 0 citations