Review
Sep 2026
Expanding the E3 Ligase Landscape: From Small Molecule to Biological Targeted Protein Degradation.
This review summarizes the development of classical small-molecule E3 ligase ligands and highlights emerging biological recruitment strategies involving antibodies, nanobodies, aptamers, peptides, and engineered proteins that provide greater programmability and selectivity.
Xuan Zhao, Yu-Han Liu, Xu-Cong Teng
· Handbook of Experimental Pha... · 0 citations