Author

Yu-Han Zhou

2 papers indexed here

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Open access Oct 2026

Integrative population genetics and multi-omics reveal IL15RA as a shared pathogenic hub in rheumatoid arthritis-related heart failure

Rheumatoid arthritis (RA) patients face a significantly elevated risk of heart failure (HF), but population-level evidence and underlying mechanisms remain unclear. We aimed to assess the RA-HF association using national data and identify dietary compounds targeting shared inflammatory pathways. We analyze...

Q. Geng, Chao-Ying Wen, Mei-Jia Yang et al. · Frontiers in Immunology · 0 citations

Open access Aug 2026

The Sesn2/Nrf2 axis suppresses oxidative stress and pyroptosis-associated signaling in LPS/nigericin-challenged alveolar macrophages.

BACKGROUND Pyroptosis is a key mechanism driving immune imbalance in sepsis, while the stress-induced protein Sestrin 2 (Sesn2) and Nuclear factor E2-related factor 2 (Nrf2) are core regulators of antioxidant defense. No existing studies have clarified the interactive regulatory effect of the Sesn2/Nrf2 axis on pyropto...

Qiong Zhang, Guanlin Zhou, Chun-Ming Gao et al. · Immunobiology · 0 citations