scLDM: a conditional diffusion framework for single-cell perturbation prediction.
MOTIVATION Accurate prediction of single-cell responses to external stimuli is pivotal for deciphering gene regulatory mechanisms and accelerating data-driven drug discovery. However, effectively capturing the complex, non-linear mapping between intrinsic cell states and external stimuli remains an open problem. RESU...
Bo-Yang Wu, Yu-Hang Liu, Yue Cheng et al.
· Bioinformatics · 0 citations