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Review Open access Aug 2026

Epigenetic regulation in transplant rejection and tolerance: mechanisms and therapeutic prospects

Epigenetics modulates gene expression and plays a pivotal role in numerous immune disorders. Over the past two decades, increasing evidence has indicated that epigenetic regulation contributes to transplant rejection and immune tolerance. Four primary epigenetic mechanisms—DNA methylation, histone modifications, chroma...

Yu-Hao Li, Shuan Ran, Yanqiang Zou et al. · 0 citations
Open access Aug 2026

Association between sodium-glucose cotransporter 2 inhibitors and the risk of chronic lower respiratory disease in type 2 diabetes mellitus: findings from two target trial emulations

Research on the association between sodium‑glucose cotransporter 2 inhibitors (SGLT-2i) and chronic lower respiratory diseases (CLRDs) in patients with type 2 diabetes (T2DM) remains limited. This study aimed to investigate this association and examine the potential modifying effects such as age, sex, and diabete...

Yu-Hao Li, Yiqiao Lv, Yong-Qi Dai et al. · 0 citations

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