Review
Open access
Sep 2026
PSMD14 as a translational target in cancer and beyond: from deubiquitination mechanisms to drug resistance and precision therapy
This review synthesizes current evidence demonstrating that PSMD14 drives therapeutic resistance across multiple malignancies by deubiquitinating and stabilizing key effectors such as E2F1, ALK2, IMPDH2, estrogen receptor α, and proteasomal components and critically evaluates the therapeutic landscape of PSMD14 inhibit...
Hong-Rui Liu, Liang Ma, Yi-Xuan Wang et al.
· Cancer Drug Resistance · 0 citations