Oxidative stress induces porcine RCAN1-1L to promote mitophagy and enhance PRRSV replication.
It is revealed that the glycoprotein 5 of PRRSV induced the porcine RCAN1-1L isoform through oxidative stress and the findings demonstrate that RCAN1-1L links mitophagy to PRRSV pathogenesis and serves as a potential antiviral therapeutic target.