Yu-Hong Ouyang

Focus on the NLRP3 inflammasome: its role in the pathogenesis and therapeutic potential of inflammation-driven osteoarthritis

Osteoarthritis (OA) is a highly heterogeneous whole-joint disease. Current treatment strategies, which primarily focus on symptomatic pain relief, are insufficient to address the therapeutic needs of patients with distinct clinical phenotypes. Accumulating evidence has demonstrated that the empirical use of conventiona...