Machine-learning models of the human microbiome are trained mostly on stool samples from single cohorts, limiting cross-body-site representation and cross-study generalization. Progress is constrained less by algorithms than by the absence of a harmonized multi-body-site corpus carrying the technical metadata needed to...
Summary Background Alzheimer’s disease and related dementias (ADRD) affect nearly 6.9 million Americans, with the number expected to triple by 2050, while disease-modifying therapies remain unavailable. Drug repurposing, which identifies new indications for already approved medications, offers a more efficient and cost...
Qiong Wu, Lu Li, Yu-Qing Lei et al.· EBioMedicine· 0 citations
ScPyviewer is a web-based viewer that ingests AnnData objects directly and reproduces the core interaction patterns of the incumbent R Shiny tools without leaving the Python stack and uniquely offers native AnnData ingestion with no Seurat conversion, and cross-dataset comparison over shared genes and matched cell-type...