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Author

Yu Huang

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Open access Sep 2026

Corpusome, a cross-body-site human microbiome corpus for representation learning

Machine-learning models of the human microbiome are trained mostly on stool samples from single cohorts, limiting cross-body-site representation and cross-study generalization. Progress is constrained less by algorithms than by the absence of a harmonized multi-body-site corpus carrying the technical metadata needed to...

Hao Xuan, Yu Huang, Jiang Bian · 0 citations
Open access Sep 2026

Discovering repurposable drugs for Alzheimer’s disease and related dementias: target trial emulation using decentralised real-world data

Summary Background Alzheimer’s disease and related dementias (ADRD) affect nearly 6.9 million Americans, with the number expected to triple by 2050, while disease-modifying therapies remain unavailable. Drug repurposing, which identifies new indications for already approved medications, offers a more efficient and cost...

Qiong Wu, Lu Li, Yu-Qing Lei et al. · 0 citations
Open access Sep 2026

scPyviewer: a Python-native interactive viewer from AnnData single-cell data

ScPyviewer is a web-based viewer that ingests AnnData objects directly and reproduces the core interaction patterns of the incumbent R Shiny tools without leaving the Python stack and uniquely offers native AnnData ingestion with no Seurat conversion, and cross-dataset comparison over shared genes and matched cell-type...

Hao Xuan, Yu Huang, Jiang Bian et al. · 0 citations

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