Author

Yu-Jian Fan

h-index 2 View on Semantic Scholar

We have 5 of 12 papers

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Review Open access Oct 2026

The Gut-Lumbar Axis: A Comprehensive Review of Mechanisms, Clinical Evidence, and Future Therapeutic Perspectives.

Low back pain (LBP) affects approximately 619 million people globally and is the leading cause of years lived with disability, yet the pathogenesis of chronic LBP remains incompletely understood despite extensive research into structural and biomechanical factors. Emerging evidence suggests that the gut microbiota, thr...

Zheng-Hao Wang, Hao Zhang, Pei-Zhou Tian et al. · Pharmacological Research · 0 citations

Review Open access Sep 2026

Microplastics and Nanoplastics in Food: Dietary Toxicology Beyond Particle Counts.

Microplastics (MPs) and nanoplastics (NPs) are ubiquitous contaminants in dietary sources, including seafood, table salt, infant formula, and drinking water. Recent stimulated Raman scattering microscopy has reported approximately 2.4 × 105 MPs and NPs per liter in selected bottled-water samples. While these estimates...

Fei-Yu Xu, Yu-Jian Fan, Xiao-Kai Guo et al. · Comprehensive Reviews in Foo... · 0 citations

Review Aug 2026

Hepatotoxicity in the Era of Precision Medicine: Toxicological Mechanisms and Management of Immune and Cell Therapy-Induced Liver Injury.

Immune checkpoint inhibitors and adoptive cell therapies have revolutionized cancer treatment, yet their success is accompanied by immune-related hepatotoxicity that can range from asymptomatic enzyme elevation to life-threatening liver failure. Unlike conventional drug-induced liver injury, immune-mediated hepatotoxic...

Yu-Jian Fan, Xiao-Kai Guo, Jiaying Lyu et al. · Medicinal research reviews (... · 0 citations

Review Open access Sep 2026

Planetary health and pharmacology: Addressing the ecological impact and circular threat of pharmaceuticals.

A mechanistic analysis of pharmaceutical ecotoxicity demonstrates that effective intervention requires targeting root causes across the pharmaceutical lifecycle rather than relying on end-of-pipe remediation, and that integrating environmental sustainability into pharmaceutical safety assessment is essential for protec...

Yu-Jian Fan, Xiao-Kai Guo, Jiaying Lyu et al. · Ecotoxicology and Environmen... · 0 citations

Review Jul 2026

The long shadow: a toxicological review of chronic exposure, biopersistence, and latent health risks of engineered nanomaterials.

An integrated risk assessment framework is proposed that combines adverse outcome pathway analysis, physiologically-based pharmacokinetic modeling, new approach methodologies, and safe-by-design principles to enable predictive hazard identification and supports evidence-based regulation of existing ENMs while enabling...

Yu-Jian Fan, Jiaying Lyu, Xiao-Kai Guo et al. · Journal of materials chemist... · 0 citations