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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Yu-jie Sheng

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Open access Jul 2026

SH3PXD2B is the critical host factor promoting the entry of mycobacteria

A genome-wide CRISPR-KO library is constructed and results indicate that SH3PXD2B is a critical host factor manipulated by M. bovis to promote macrophage phagocytosis and inhibit migration, thereby facilitating bacterial invasion and reveal a new pathogenic strategy.

Donghui Liu, Ting Zhang, Yu-jie Sheng et al. · 0 citations

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