Neural–Tumor and Microenvironmental Interactions in Brain Metastases from Lung Cancer: From Blood–Brain Barrier Traversal to Adaptation within the Brain
Brain metastases from lung cancer do not merely reflect passive tumor growth after entry into the central nervous system. Rather, their development is a dynamic process involving transvascular entry into the brain, remodeling of the intracranial microenvironment, metabolic adaptation, and changes in neural function. Ad...