Targeting NCAM1/FGFR1 Signaling to Alleviate Sleep Disturbance-Induced Neuroinflammation in the Hypothalamus
Highlights What are the main findings? Sleep disturbance (SD) induces neuroinflammation and neuronal injury in the hypothalamus, triggering microglial activation and facilitating a pro-inflammatory phenotypic transformation. SD selectively enhances pro-inflammatory responses and functional impairment in multiple hypoth...