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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Yu-Jie Zhou

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Sep 2026

Novel Coumarin Derivatives Containing Oxazole/Isoxazole/Pyrazole Groups as Antifungal Agents: Design, Synthesis, Quantitative Structure–Activity Relationships, and Preliminary Mechanistic Insights

Plant pathogenic fungi pose a significant threat to global crop productivity and food security. Herein, we report the design and synthesis of 55 coumarin–oxazole, −isoxazole, and −pyrazole hybrids as novel antifungal agents. Most derivatives exhibited notable potency, with C1, C4, and C5 showing strong activity again...

Peng Dai, Yang Hong, Yue Zhang et al. · 0 citations
Aug 2026

Design, Synthesis, Antifungal Activity, and Action Mechanism of Indole-Oxazole Compounds as Potential Fungicides.

Starting from 1H-indole-3-carbaldehyde, 19 indole oxazole alkaloid analogues were synthesized in excellent yields. The results of bioassays showed that compound Z-2 possessed potent activity against Rhizoctonia solani and Botrytis cinereaPers with EC50 values of 7.03 and 13.5 mg/L, respectively. Compound Z-3 (EC50 = 6....

Wei Zhan, Zhiyang Mei, Mingxia Dan et al. · 0 citations

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