Simultaneous synthesis of resveratrol by dual-compartment metabolic engineering in Saccharomyces cerevisiae.
Resveratrol, a plant-derived polyphenolic compound, is widely used in medicine, health care, and nutrition. Synthetic biologyenables the microbial synthesis of resveratrol as apromising alternative to traditional plant extraction. However, an insufficient precursor supply remains a critical bottleneck limiting the over...