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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Yu Liu

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2 papers indexed here

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Open access Oct 2026

IGF2BP1 in 17q-gain cooperates with MYCN to regulate purine biosynthesis and immunotherapy efficacy in neuroblastoma.

Concurrent chromosomal 17q-gain and MYCN amplification define a subset of neuroblastoma associated with particularly adverse clinical outcomes. However, how these genetic alterations synergize to promote tumor progression and whether their cooperation confers therapeutic vulnerabilities remain elusive. We herein perfor...

Jia-Xu Liu, Ying-Zhe Fang, Rong-Rong Fan et al. · 0 citations
Open access Oct 2026

FOXP4 maintains redox homeostasis in medulloblastoma via upregulation of SLC7A11 to suppress ferroptosis

This study demonstrates that FOXP4 is overexpressed in MB, especially in the high-risk Group 3 (G3) subtype, and correlates with poor patient prognosis, and provides a mechanistic rationale for targeting this pathway to enhance the efficacy of ferroptosis-inducing therapies, such as sorafenib, in high-risk MB.

Jun-Jie Jing, Qing-Shuang Zhao, Hou-Shun Fang et al. · 0 citations

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