Open access
Oct 2026
A CD68-expressing tissue-homing subset in peripheral CD8+ T cells predicts response to anti-PD-1 therapy in lung cancer
T-cell function is regulated by immunometabolism, and lysosomes are signaling hubs. CD68 (LAMP4), traditionally regarded as a monocyte/macrophage marker, has been largely neglected in T cell biology. We aimed to assess the link between CD68 expression in T cells and anti-PD-1 response in lung cancer, and its pote...
Ying Wang, Jing Huang, Zheng-Yi Sun et al.
· Frontiers in Immunology · 0 citations