Emerging role of cGAS-STING in the pathogenesis of allergic diseases.
The cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) signaling pathway, classically recognized as a crucial cytosolic DNA-sensing mechanism in innate antiviral immunity, is now emerging as a pivotal regulator of sterile inflammation and immune dysregulation. Recent evidence has shifted the paradigm,...