Yu-Nan Chen

Sequencing Deoxyuracil at Single-Base Resolution via a Hydrazine Reagent-Induced U-to-A Transition

Uracil is a canonical base in RNA, yet its presence in DNA represents the most common non-canonical modification, with broad implications for diverse physiological processes. However, due to the lack of suitable analytical methods, the distribution and biological functions of deoxyuracil (dU) in the genome remain lar...