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Author

Yu-Ning Liao

2 papers indexed here

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Oct 2026

Deubiquitination of WBP11 governs OPLAH-mediated glutathione biosynthesis to suppress triple programmed cell death in prostate cancer.

Prostate cancer (PC) is one of the most common male cancers. Cancer cells are well known for their capacity to avoid programed cell death (PCD) via a variety of molecular pathways, allowing them to survive oncogenic stress and therapeutic challenges. Although oncogenic splicing factors are frequently dysregulated in tu...

Xue-Fen Zhuang, Wan-Ying He, Jiang-Yu Zhang et al. · 0 citations
Sep 2026

Saquinavir inhibits pyroptosis by regulating NLRP3 degradation to alleviate acute lung injury.

BACKGROUND In critically ill patients, sepsis can precipitate acute lung injury (ALI), a syndrome with high incidence in intensive care settings. Pyroptosis plays an important role in ALI, highlighting its potential as a drug target. The NLRP3-mediated classical pyroptosis pathway is notably implicated in this pathogen...

Tian-Yu Kong, Xiao-Yue He, Zi-Xian Yin et al. · 0 citations

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