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Author

Yu-Ping Qi

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Oct 2026

ED-71 ameliorates oxeiptosis-associated signaling in BMSCs under diabetic osteoporosis by alleviating PKM2-associated metabolic dysregulation and mitochondrial dysfunction.

ED-71 may alleviate mouse DOP by reducing PKM2 expression to correct metabolic reprogramming and mitochondrial dysfunction, thereby suppressing oxeiptosis and restoring HG-treated BMSCs' osteogenic potential, offering a novel mechanistic foundation for its therapeutic application.

R. Yuan, Ya-Jun Cui, Jun Sun et al. · 0 citations

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