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Author

Yu-Qi Li

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Open access Sep 2026

BDE-47 and male infertility: integrated network toxicology, single-cell transcriptomics, and in vitro evidence of GSTM1 downregulation and ferroptosis-related molecular remodeling in Leydig cells

BDE-47-related molecular evidence and human NOA-associated evidence showed molecular convergence around GSTM1 and ferroptosis-related molecular features in a Leydig-cell context, but this does not establish direct binding, GSTM1-mediated effects, ferroptotic cell death, or a causal relationship between BDE-47 exposure...

Xin-Yao Zhu, Shuang Wang, Tao Li et al. · 0 citations
Sep 2026

CDKL1 facilitates tumorigenesis and metastasis of bladder urothelial carcinoma by activating SIRT1/Wnt/β-catenin signaling.

Bladder urothelial carcinoma (BUC) is a common malignancy characterized by high recurrence and progression, and patients with advanced disease often have poor outcomes due to therapeutic resistance and limited targeted treatment options. In this study, we investigated the role of cyclin-dependent kinase-like 1 (CDKL1)...

Hua-Jun Tan, Yun Zhang, Yong-Qi Long et al. · 0 citations

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