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Author

Yu-Qian Yan

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Open access Aug 2026

SPOP-mediated ZMYND8 ubiquitination and phase separation exclusion drives mTOR inhibitor resistance in kidney cancer

mTOR inhibitors including everolimus and temsirolimus have been approved by US FDA for treatment of clear cell renal cell carcinoma (ccRCC) in clinic. However, resistance to these drugs has been inevitable and the underlying mechanism remains poorly understood. Histone modifier ZMYND8 paradoxically acts as a transcript...

Bo Tang, Rui Sun, Jing-Wei Shao et al. · 0 citations
Oct 2026

Expression and Purification of Staphylococcal Enterotoxin B and Detection of SEB-Specific IgG Antibodies in Allergic Children.

ObjectiveThis study aims to express and purify staphylococcal enterotoxin B (SEB) and to detect and analyze the levels of SEB-specific IgG antibodies in the serum of children with food or aeroallergen allergies using an enzyme-linked immunosorbent assay (ELISA).MethodsSEB protein was expressed and purified in a recombi...

Hui-Xin Gao, Yu-Qian Yan, Qing-Ling Ma et al. · 0 citations

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