Author

Yu-Qin Sun

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Review Open access Sep 2026

Anti-CD19 CAR T-cell therapy for autoimmune diseases: from exploratory clinical trials to quantitative pharmacodynamic modeling development

Anti-CD19 CAR T-cell therapy has produced major advances in treating hematologic malignancies. Recently, researchers have explored its use in autoimmune diseases. However, the complex pathogenesis and high heterogeneity of these disorders create substantial uncertainty about treatment efficacy and safety in clinical se...

Yu-Qin Sun, Xiao Heng, G. Hu et al. · Frontiers in Immunology · 0 citations

Case report Open access Sep 2026

Early-onset parkinsonism as a presenting feature of suspected type 1 Gaucher disease with two pathogenic GBA1 variants: a case report

Parkinson's disease (PD) is a common neurodegenerative disorder, and pathogenic variants in GBA1 are among its most frequent genetic risk factors. Biallelic pathogenic GBA1 variants cause Gaucher Disease (GD). In patients with parkinsonism and two detected GBA1 variants, the absence of biochemical confirmation and alle...

Yu-Qin Sun, Rui-Han Ni, Yun-Li Yu · Frontiers in Neuroscience · 0 citations